Modeling Alveolar Gas Transport during Liquid Ventilation

نویسندگان

  • Vinod Suresh
  • Joseph C. Anderson
  • Ronald B. Hirschl
چکیده

Introduction During gas ventilation, gas transport within the alveolar sac is dominated by diffusion. In liquid ventilation, perfluorocarbon (PFC) introduced into the alveolar space acts as a diffusion barrier to gas transport since the diffusivities of oxygen and carbon dioxide in this medium are four orders of magnitude lower than in air. Therefore convection in the PFC layer resulting from the oscillatory motions of the alveolar sac during ventilation can significantly affect gas transport. We study these effects in both partial (PLV) and total liquid ventilation (TLV) using a simplified theoretical model.

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تاریخ انتشار 2002